Protplex
Searches over 240,000 Protein Data Bank structures using plain-language questions.
What Protplex can do in ChatGPT
Search the Protein Data Bank in plain words.
Plain-Language Search
Describe the structure you need instead of writing a query.
240,000+ Structures
Search across a large set of PDB entries.
Function And Chemistry
Filter by what a protein does and its chemistry.
Ligand Search
Find structures with a specific cofactor or bound ligand.
Organism Filter
Narrow results to a species or group, such as archaea.
You stay in control
You approve access, and you can disconnect Protplex at any time.
Apps 1
What Protplex does in ChatGPT
The Protplex plugin makes the Protein Data Bank searchable in plain language from ChatGPT. Instead of building a complex database query by hand, you describe the kind of protein structure you want, and it finds matching entries among more than 240,000 structures in the PDB.
Each structure is described by a condensed profile covering its shape, its function and its biochemistry. You can search across function, structure, chemistry, source organism, assembly, bound ligands and the conditions of the experiment, and combine several of these in one question.
That lets you ask very specific questions, such as which enzymes from archaea contain the F430 cofactor, and get a list of fitting structures back. The listing is short and focuses on search only, so it does not describe downloading files, viewing 3D models or any account features.
Who it is for
- Structural biologists
- Biochemistry researchers
- Graduate students in life sciences
How to add Protplex to ChatGPT
- Open the Protplex listing in ChatGPT ↗.
- Click Install plugin.
- Sign in to your Protplex account when asked and approve the access it requests.
- Start a chat and ask for what you need, mentioning Protplex if ChatGPT does not pick it up.
- To stop, disconnect Protplex under apps in your ChatGPT settings.
Questions about Protplex
What is the Protplex ChatGPT plugin?
The Protplex plugin makes the Protein Data Bank searchable in plain language from ChatGPT. Instead of building a complex database query by hand, you describe the kind of protein structure you want, and it finds matching entries among more than 240,000 structures in the PDB. It is listed in ChatGPT's plugin marketplace under Education & Research.
What can I ask Protplex to do in ChatGPT?
For example: "Find archaeal enzymes that contain the F430 cofactor", "Show human kinase structures bound to an inhibitor", "Find cryo-EM structures of membrane transporters".
Who makes the Protplex plugin for ChatGPT?
The ChatGPT listing names Straintest as the developer. The version listed on 8 October 2026 was 1.0.0.
How do I add Protplex to ChatGPT?
Open the Protplex listing in ChatGPT, click Install plugin, sign in to your Protplex account and approve the access it asks for. Then ask for what you need in a chat, mentioning Protplex if ChatGPT does not pick it up.
Can Protplex change things in my account, or only read?
It searches profiles of Protein Data Bank structures. The listing does not describe access to any personal account.
Who is the Protplex plugin for?
Structural biologists, biochemistry researchers and graduate students in life sciences.
How many structures can Protplex search?
The listing says it covers more than 240,000 PDB structures.
What can I filter on in Protplex?
Function, structure, chemistry, organism, assembly, ligands and experimental context.
Does Protplex see my ChatGPT chats?
When Protplex is connected, ChatGPT may share the parts of your chats and memories that matter for a request with Protplex. What Protplex does with that data falls under its own terms and privacy policy. ChatGPT keeps your training-data settings, and you can disconnect at any time.
How do I disconnect Protplex from ChatGPT?
Open your ChatGPT settings, go to apps, and disconnect Protplex. You can reconnect later from the listing.
What are alternatives to Protplex in ChatGPT?
Similar plugins in the ChatGPT marketplace include italki language learning, Preply Language Tutor Finder and Sider Scholar. Each has its own page in this directory.
Privacy and your data
When Protplex is connected, ChatGPT may share the parts of your chats and memories that matter for a request with Protplex. What Protplex then does with that data falls under its own terms and privacy policy, not only OpenAI's. ChatGPT keeps your training-data settings for data that comes from connected apps, and you can disconnect at any time.
Protplex privacy policy ↗Protplex terms ↗OpenAI: apps in ChatGPT ↗